Peptidomimetic growth hormone secretagogues. Design considerations and therapeutic potential

J Med Chem. 1998 Aug 13;41(17):3103-27. doi: 10.1021/jm970342o.

Authors

R P Nargund¹, A A Patchett, M A Bach, M G Murphy, R G Smith

Affiliation

¹ Departments of Medicinal Chemistry, Clinical Pharmacology, Clinical Sciences, and Biochemistry and Physiology, Merck Research Laboratories, P.O. Box 2000, Rahway, New Jersey 07065, USA.

PMID: 9703459
DOI: 10.1021/jm970342o

No abstract available

Publication types

Review

MeSH terms

Amino Acid Sequence
Animals
Drug Design
Growth Hormone-Releasing Hormone / chemical synthesis*
Growth Hormone-Releasing Hormone / chemistry
Growth Hormone-Releasing Hormone / pharmacology
Growth Hormone-Releasing Hormone / physiology*
Hormones / chemical synthesis*
Hormones / chemistry
Hormones / pharmacology
Human Growth Hormone / metabolism*
Human Growth Hormone / therapeutic use
Humans
Hypothalamo-Hypophyseal System / physiology
Molecular Sequence Data
Oligopeptides / chemical synthesis*
Oligopeptides / chemistry
Oligopeptides / pharmacology
Protein Conformation
Receptors, Somatotropin / chemistry
Receptors, Somatotropin / physiology*

Substances

Hormones
Oligopeptides
Receptors, Somatotropin
Human Growth Hormone
Growth Hormone-Releasing Hormone